Abstract: Instrumented indentation tests were applied to five metals, 6061 aluminum alloy, S45C carbon steel,SS316 stainless steel, SS304 stainless steel and brass, and then the elastic modulus of five metals were calculated by Energy-based method and and Oliver-Pharr method. The calculated results by two method were compared to that from standard uniaxial tensile test. The results show that the relative errors of elastic modulus between Energy-based method and tensile test were 7.65%,3.99%,3.25%,-1.12% and 16.47%, respectively. Compared with the Oliver-Pharr method, Energy-based method possessed higher precision and were better enough to satisfy the need of engineering application.