• CSCD中国科学引文数据库来源期刊
  • 中文核心期刊
  • 中国机械工程学会材料分会会刊
  • 中国科技核心期刊
高级检索

溶胶-凝胶结合共沉淀法制备球形生物活性玻璃粉体

武涛, 张兴凯, 范德增

武涛, 张兴凯, 范德增. 溶胶-凝胶结合共沉淀法制备球形生物活性玻璃粉体[J]. 机械工程材料, 2016, 40(6): 69-73. DOI: 10.11973/jxgccl201606015
引用本文: 武涛, 张兴凯, 范德增. 溶胶-凝胶结合共沉淀法制备球形生物活性玻璃粉体[J]. 机械工程材料, 2016, 40(6): 69-73. DOI: 10.11973/jxgccl201606015
WU Tao, ZHANG Xing-kai, FAN De-zeng. Spherical Bioactive Glass Powders Prepared by Sol-gel Method and Co-precipitation Method[J]. Materials and Mechanical Engineering, 2016, 40(6): 69-73. DOI: 10.11973/jxgccl201606015
Citation: WU Tao, ZHANG Xing-kai, FAN De-zeng. Spherical Bioactive Glass Powders Prepared by Sol-gel Method and Co-precipitation Method[J]. Materials and Mechanical Engineering, 2016, 40(6): 69-73. DOI: 10.11973/jxgccl201606015

溶胶-凝胶结合共沉淀法制备球形生物活性玻璃粉体

基金项目: 

国家自然科学基金资助项目(50830106)

详细信息
    作者简介:

    武涛(1989-), 男, 河北邯郸人, 硕士研究生。

  • 中图分类号: R318.08

Spherical Bioactive Glass Powders Prepared by Sol-gel Method and Co-precipitation Method

  • 摘要: 结合溶胶-凝胶法和共沉淀法制备出了三种硅含量不同的生物活性玻璃(BAG)湿凝胶, 然后分别用真空冷冻干燥和真空加热干燥方法对湿凝胶进行干燥,得到了球形BAG粉体(58S粉体, 68S粉体和77S粉体), 研究了分散剂聚乙二醇(PEG)、硅含量、干燥方法对BAG粉体粒径、形貌的影响; 然后将68S粉体在模拟体液中进行矿化试验, 研究了BAG粉体的矿化性能。结果表明:加入PEG可以有效控制BAG粉体的形状和粒径, 使粉体颗粒趋于球形; 68S粉体的粒径最小, 表面最光滑, 球形度最好; 真空冷冻干燥可以有效抑制湿凝胶在干燥过程中的团聚; 矿化后的BAG粉体表面形成了一层碳酸羟基磷灰石(HCA)层, 具有良好的生物活性。
    Abstract: Sol-gel method and co-precipitation method were combined to prepare bioactive glass (BAG) wet get with different amounts of silicon, and the wet get was dried at vacuum freeze-drying and vacuum heat-drying modes to prepare spherical BAG powders (58S powders, 68 powders and 77S powders). The effects of dispersant PEG (polyethylene glytol), silicon content and drying modes on the size and morphology of BAG powders were studied. And then, mineralization test was carried out by adding 68S powders to simulated body fluid (SBF). The results show that PEG can control effectively the shape and size of BAG powders, and make the particles keep sphericity. 68S powders has the smallest size, the most smooth surface and the best degree of sphericity. Vaccum freeze-drying can effectively restraine the aggregation of wet get during drying. Carbonate hydroxyl apatite(HCA) was formed on BAG powder surface after mineralization, which made BAG powders have good biological activity.
  • [1] HENCH L L. Bioceramics: from concept to clinic[J]. Journal of the American Ceramic Society, 1991, 74(7): 1487-1510.
    [2] HULBERT S F, HENCH L L, FORBERS D, et al. The story of bioceramics [J]. Ceramics International, 1982, 8(4):131-140.
    [3] KOKUBO T, ITO S, SHIGEMATSU M, et al. Mechanical properties of a new type of apatite-containing glass-ceramic for prosthetic application[J]. Journal of Materials Science, 1985, 20(6): 2001-2004.
    [4] 陶莹,马壮,孙方红,等. 以粉煤灰和Al-TiO2-B2O3为原料制备玻璃/陶瓷复合涂层的组织及耐磨性能[J].机械工程材料,2014,38(9):29-33.
    [5] 张娟娟,陈晓峰,林才,等. 聚乙二醇为分散剂制备纳米生物活性玻璃粉体[J]. 硅酸盐通报,2010,29(2):257-261.
    [6] CHEN X, MENG Y, LI Y. Investigation on bio-mineralization of melt and sol-gel derived bioactive glasses [J]. Applied Surface Science, 2008, 255 (2): 562-564.
    [7] ZHONG J P, GREENSPAN D C. Processing and properties of sol-gel bioactive glasses [J]. J Biomed Mater Res, 2000, 53(6):694-701.
    [8] 李延明. 生物玻璃的合成及其性能的研究[D].哈尔滨:哈尔滨工程大学,2013:20-22.
    [9] DE OLIVEIRA A A R, DE CARVALHO B B, MANSUR H S, et al. Synthesis and characterization of bioactive glass particles using an ultrasound-assisted sol-gel process: engineering the morphology and size of sonogels via a poly (ethylene glycol) dispersing agent[J]. Materials Letters, 2014, 133: 44-48.
    [10] KIM I Y, KAWACHI G, KIKUTA K, et al. Preparation of bioactive spherical particles in the CaO-SiO2 system through sol-gel processing under coexistence of poly (ethylene glycol)[J]. Journal of the European Ceramic Society, 2008, 28(8): 1595-1602.
    [11] 周洪兆,朱慎林. 分散剂对超细硫酸钡粉体制备的影响[J].机械工程材料,2005,29(4):17-19.
    [12] 邹同征,涂江平,夏正志,等. 聚乙二醇为分散剂的沉淀法制备IF-MoS2[J].无机化学学报,2005,21(8):1170-1174.
    [13] LEI B, CHEN X, WANG Y, et al. Synthesis and in vitro bioactivity of novel mesoporous hollow bioactive glass microspheres[J].J Materials Letters,2009,63(20):1719-1721.
    [14] 高雪艳,凌程凤,谈技,等.冷冻干燥法制备纳米氧化镁条件的研究[J].海湖盐与化工,2005,34(5):10-11.
    [15] 蔡小先,周大利,胡驰,等.溶胶-冷冻干燥法制备纳米VO2研究[J].四川有色金属,2009(1):15-19.
    [16] KOKUBO T, ITO S, HUANG E T, et al. Ca, P-rich layer formed on high-strength bioactive glass-ceramic A-W[J]. J Biomed Mater Res, 1990,24(3):331-343.
    [17] PERTL O, ZANOTTO E D, HENCH L L. Highly bioactive P2O5-Na2O-CaO-SiO2 glass-ceramics[J]. J Non-crystal Solids, 2001, 292(123):115-126.
    [18] ANDRADE A, VALERIO P, GOES A M, et al. Influence of morphology on in vitro compatibility of bioactive glasses[J]. J Non-crystalline Solids, 2006, 352(32): 3508-3511.
    [19] OLIVEIRA J M, CORREIA R N, FERNANDES M. Effects of Si speciation on the in vitro bioactivity of glasses[J]. Biomaterials, 2002, 23(2): 371-379.
    [20] LEONELLI C, LUSVARDI G. Synthesis and characterization of cerium-doped glasses and in vitro evaluation of bioactivity[J].J Non-crystalline Solids, 2003, 316(2): 198-216.
计量
  • 文章访问数:  3
  • HTML全文浏览量:  0
  • PDF下载量:  0
  • 被引次数: 0
出版历程
  • 收稿日期:  2016-03-14
  • 刊出日期:  2016-06-19

目录

    /

    返回文章
    返回