Abstract: ZK60 magnesium alloy was rolled at different deformation temperatures (275-350℃) and different strain rates (5-25 s^-1) by a single pass rolling process with a large reduction of 80%. The effects of deformation temperature and strain rate on microstructure and tensile properties of the alloy were studied. The results show that the recrystallization volume fraction of the alloy increased with the increase of deformation temperature and stain rate. When the deformation temperature was not higher than 300℃, the recrystallization grain size decreased and then increased, the tensile strength increased and then decreased, and the elongation increased with the increase of strain rate. When the temperature was higher than 300℃, the recrystallization grain size increased and then decreased and then increased, the tensile strength decreased and then increased and then decreased, and the elongation increased with the increase of stain rate. After being rolled at 300℃ and strain rate of 10 s^-1, the as-rolled ZK60 magnesium alloy sheet had a relatively optimal comprehensive tensile property with the tensile strength of 358 MPa and the elongation of 21.5%.