Abstract: The quasi-static tensile tests were conducted on smooth sample and notched sample of superalloy GH4169 under strain rates of 0.000 1-0.010 0 s^-1 at room temperature by the material testing machine. The dynamic tensile and compression tests were conducted under strain rates of 1×10²-4×10³ s^-1 at 20-400℃ by split Hopkinson tension and pressure bar setup. The quasi-static and dynamic true stress-true strain curves and failure strains were obtained. Based on the experimental data, the parameters of Johnson-Cook material model and failure model were confirmed by the stepwise fitting method. The dynamic compression behavior was simulated by Johnson-Cook model, and verified by the experiment. The results show that the yield strength of superalloy GH4169 increased with the increase of strain rate, and decreased with the increase of test temperature; the alloy had a strain rate strengthening effect and a temperature softening effect. The simulation results were in good agreement with the experimental results, and the maximum relative error of the true stress-strain curve was 5.91%, indicating that the Johnson-Cook constitutive model could describe the dynamic mechanical behavior of superalloy GH4169 well.