Abstract: GH4169 alloy was prepared by selective laser melting (SLM) technique, and the heat treatments of hot isostatic pressing+aging and hot isostatic pressing+solution+aging were applied to control the precipitation of δ phase. The effect of δ phase on stress rupture properties of the alloy was investigated. The results show that the microstructure of SLM forming GH4169 alloy consisted of equiaxed grains and annealing twins after two heat treatments. A large number of rod-like and continuous granular δ phases precipitated at grain boundaries of the alloy after hot isostatic pressing+solution+aging treatment. The stress rupture life at 650 ℃/690 MPa of the alloy heat-treated by hot isostatic pressing+solution+aging was about half of that of the alloy heat-treated by hot isostatic pressing+aging, the precipitation of δ phase was the main reason for the lower stress rupture life of the alloy. The stress rupture lives of alloys after two heat treatments highly exceeded the standard requirements of the forging, and the fracture feature was intergranular fracture.