Abstract: The establishment of a 3D random model of foam metal sandwich panel based on MATLAB software was described in detail. The quasi-static compression performance of the foam metal sandwich panel was simulated by ANSYS finite element software, and was compared with the test results. The dynamic mechanical properties of the foam aluminum sandwich panel under impact load were studied by the established 3D random model. The results show that the quasi-static compression true stress-true strain curves simulated by the random model were basically consistent with the test results, all having elastic stage, yield stage and compaction stage; the relative error was smaller than 10%, verifying the effectiveness and reliability of the model. After impact at the same initial velocity (80, 100, 200 m·s^-1), the peak stress and absorbed energy of the foam aluminum sandwich panel with porosity of 60% were lower than those with porosity of 50%. The peak initial stress, platform stress and the absorbed energy of the foam aluminum sandwich panel with the same porosity increased with initial impact velocity.