Abstract: The effects of spindle speed (300, 500, 650, 800, 1 200 r·min^-1), milling feed (0.030, 0.045, 0.060, 0.075, 0.090 mm·r^-1) and single pass milling depth (0.20, 0.35, 0.50, 0.65, 0.80 mm) on the machined surface integrity of nickel-based superalloy FGH4113A were investigated by milling tests. The results show that with increasing milling feed or single pass milling depth, the defects on the machined surface, surface roughness and hardness increased, and the surface residual stress gradually changed from compressive stress to tensile stress. With increasing spindle speed, the machined surface defects, surface roughness, hardness and residual compressive stress all decreased. When the spindle speed exceeded 800 r·min^-1, the single pass milling depth was less than 0.35 mm, and the milling feed was controlled below 0.045 mm·r^-1, the machined surface had good quality with surface roughness R_a of about 0.40 μm, compressive residual stress and no obvious hardening layer existing.