Abstract: The method of powder metallurgy was used to prepare nuclear fusion reactor first-wall structural materials———9Cr-ODS RAFM steel, the microstructure of powders after alloying and sintered specimen was analyzed by using XRD, OM, SEM and EDS, and the effects of ratio of grinding media to material on powders characteristics and sintering temperature on the microstructure and tensile strength of sintered bodies were discussed. The results show that the alloying was better and the powders presented flake and uniform size when the ratio of grinding media to material was 20∶1 and ball-milling time was 48 h. When the sintering temperature was 1300-1390 ℃, the porosity of sintered bodiesde creased, microstructure was more uniform, tensile strength increased gradually from 376.0 MPa to 562.9 MPa and the elongation increased in step with tensile strength, its maximum was 20.2%.