Abstract: Base on failure analysis and stress distribution analysis of the stuffing box using the Lame Formula and software ANSYS in predigested model,it is found that the composition of the material accorded with the requirement for stuffing box,and the microstructure with few impurity was qualified.The fracture of stuffing box was caused by fatigue,which resulted from the maximum stress concentration on the centripetal border of the oil hole.Increasing the distance from oil hole to inner annulus of the stuffing box can prevent the fatigue.