Abstract: Uniaxial symmetrical strain-controlled fatigue tests were conducted at room temperature for rolled aluminum alloy plates along three typical directions,the rolling direction (RD),the direction at 45° angle with the rolling direction (MD),and the transverse direction (TD),to study the differences of cyclic deformation and fatigue lives of the 5083H111 alloy plates. The results show that the rolled alloy plates were characterized by obvious cyclic hardening in three directions-that was to say the responded stress amplitude increased progressively with the increase of the cycles number. The larger the applied strain amplitudes,the larger the responded stress amplitudes. However,the differences among the ε-Nf curves in three directions were not obvious. The fatigue lives of the alloy plates were predicted by a three-parameter power function failure model,and the predicted lives were in good agreement with the experimental ones.