Preparation and Anti-Coagulant Property of TiO<sub>2</sub> Film Deposited on Nanocrystalline Titanium Substrate Surface

ZHAO Guang-wei; SHAO Hong-hong; YU Chun-hang; XU Xiao-jing; DU Hong; ZHAI Rui; ZHENG Qian-wen

Materials and Mechanical Engineering > 2010 > 34(4): 76-78.

ZHAO Guang-wei, SHAO Hong-hong, YU Chun-hang, XU Xiao-jing, DU Hong, ZHAI Rui, ZHENG Qian-wen. Preparation and Anti-Coagulant Property of TiO₂ Film Deposited on Nanocrystalline Titanium Substrate Surface[J]. Materials and Mechanical Engineering, 2010, 34(4): 76-78.

Citation:

PDF (837 KB)

Preparation and Anti-Coagulant Property of TiO₂ Film Deposited on Nanocrystalline Titanium Substrate Surface

More Information

Received Date: September 13, 2009

Graphical Abstract

Abstract

Abstract

TiO2 thin films were deposited on nanocrystalline titanium and coarse-grained commercial pure titanium by DC reactive magnetron sputtering.The structure of the films was analyzed by XRD.The anti-coagulant properties of different thin films were investigated through dynamic clotting time and platelet adhesion in vitro respectively.The results show that thin films on nanocrystalline titanium had finer,more uniform and compact grains than those on coarse-grained commercial pure titanium.The TiO2 thin films structure were composed of rutile and anatase.Nanocrystallization of Ti substrate could improve the anti-coagulant properties of itself and TiO2 thin films.
- TiO2 thin film,
- nanocrystalline Ti,
- anti-coagulant property,
- DC reactive magnetron sputtering

FullText(HTML)

References (14)

References

[1]	OKAZAKI Y,GOTOH E.Metal release from stainless steel,Co-Cr-Mo-Ni-Fe and Ni-Ti alloys in vascular implants[J].Corrosion Science,2008,50(12):3429-3428.
[2]	刘华,崔春翔,申玉田.生物医用钛合金表面改性[J].河北工业大学学报,2003,32(5):17-22.
[3]	王勇,曲华,齐国先.钴合金裸支架与雷帕霉素药物涂层支架在冠心病患者中的应用对比研究[J].中国医科大学学报,2008,37(3):374-379.
[4]	HIETALA E M,MAASILTA P,VALIMAA T.Platelet responses and coagulation activation on polylactide and heparin-polycaprolactone-L-lactide-coated polylactide stent struts[J].Journal of Biomedical Materials Research Part A,2003,67:785-791.
[5]	O’BRIEN B,STINSON J,CARROLL W.Development of a new niobium-based alloy for vascular stent applications[J].Journal of the Mechanical Behavior of Biomedical Materials,2008,1(4):303-312.
[6]	RACK H J,QAZI J I.Titanium alloys for biomedical applications[J].Materials Science and Engineering C,2006,26(8):1269-1277.
[7]	LATYSH V,KRALLICS G,ALEXANDNOY I,et al.Application of bulk nanostructured materials in medicine[J].Current Applied Physics,2006,6(2):262-266.
[8]	YU A,VINOGRADOV V V,STOLYAROV S,et al.Cyclic behavior of ultrafine-grain titanium produced by severe plastic deformation[J].Materials Science and Engineering A,2001,318(1/2):163-173.
[9]	BALYANOV A,KUTNYAKOVA J,AMIRKHANOVA N A,et al.Corrosion resistance of ultra fine-grained Ti[J].Scripta Materialia,2004,51(3):225-229.
[10]	王贺权,巴德纯,沈辉,等.总气压对直流反应磁控溅射制备TiO2薄膜的光学性质的影响[J].真空科学与技术学报,2005,25(1):65-68.
[11]	XU Xiao-jing,SHAO Hong-hong,GAO Jian-chang,et al.Effect of SiC film on tensile properties of nanostructured Ti produced by compressive deformation at liquid-nitrogen temperature[J].Materials Science and Engineering A,2008,493:195-201.
[12]	CHIGNIER E,GUIDOLLER J,HCYNEN Y,et al.Macromolccular,histological ,ultrastructural and immunocytochemical characteristics of the neointima developed within in PTFE vascular grafts .Experimental study in dogs[J].Journal of Biomedical Materials Research,1983,17:623-636.
[13]	耿方,石萍,CHENG F T.NiTi形状记忆合金表面TiO2薄膜的制备及其血液相容性[J].中国有色金属学报,2004,14(9):1575-1579.
[14]	张峰,李昌荣,王向晖.氧化钛薄膜相容性机理探讨[J].生物医学工程学杂志,2000,17(2):146-152.

Cited By

Get Citation

PDF

XML

Article views (2) PDF downloads (0)

Turn off MathJax

Article Contents

Abstract

References

Preparation and Anti-Coagulant Property of TiO2 Film Deposited on Nanocrystalline Titanium Substrate Surface

Abstract

References

Catalog

Export File

Citation

Format

Content

Preparation and Anti-Coagulant Property of TiO₂ Film Deposited on Nanocrystalline Titanium Substrate Surface